Interpretation, Extrapolation, and Perturbation of Single Cells#
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Documentation Contents#
📚 A Living Catalogue of Single-Cell Perturbation Methods
Single-cell genomics is moving beyond cell atlases toward models that interpret and extrapolate cellular responses to perturbations. This webpage lists technical details for more than 152 of these methods. Moreover, as part of a perspective, it aims to help researchers pick the right tool and highlight open challenges for future method advances.
🎯 Mission: Helping researchers navigate the rapidly evolving landscape of single-cell perturbation analysis
An ontology for modelling alterations and response#
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Citation#
Dimitrov*, D., Schrod*, S., Rohbeck, M., and Stegle, O. Interpretation, extrapolation and perturbation of single cells. Nat Rev Genet (2026). https://doi.org/10.1038/s41576-025-00920-4